課 程 資 訊 / COURSE INF.

TAIPEI MEDICAL UNIVERSITY

學程課程地圖

Required Course

1. Research ethics

  • Syllabus：
    • To introduce basic knowledge of research ethics.
    • To understand humanity and social issues of research ethics.
    • To develop critical thinking about research ethics issues.
    • To apply ideas and principles of research ethics to personal work or research.
  • Credits：0
  • Semester：First Semester or Second Semester in Grade 1 or Grade 2 (either one)
  • Language：Chinese、English
  • Others：All TMU graduate students are required to complete this course before graduation.

2. Translational medicine

  • Syllabus：
    • This course is mainly for the physicians who are interested in pursuing a doctoral degree of biomedical research and introduces the concept of translational research for students.
    • The lecture includes research of translational medicine in different fields, such as basic immunology, immunotherapy, genetic research, proteomics, etc.
  • Credits：3
  • Semester：Grade 1, First Semester
  • Language：English

3. Seminar in translational medicine

  • Syllabus：
    • Each week, a student should make an oral presentation which is related to the previous lecture. There is 40 minutes for presentation and 10 minutes for discussion.
    • We will invite the teachers in our program to join the seminar (a teacher from Academia Sinica and a teacher of National Taiwan University or Kaohsiung Medical University invited by presented student) to serve as committees. Papers/references will be provided by teachers in this course.
    • The committees and other students will give a scores based on the performance of presented student in oral presentation and discussion.
  • Credits：4
  • Semester：Each semester 1 credit in Grade 1 and 2
  • Language：English

4. Rotation

  • Syllabus：This course focuses on field training, where students will be assigned to TMU’s clinical trial center for visits and discussions, including interviews, case-based discussion and group-sharing with teachers and staffs, enabling students to understand the practices and get more experience of clinical trials.
  • Credits：2
  • Semester：Each semester 1 credit in Grade 1
  • Language：English

5. Molecular medicine

  • Syllabus： The lecture course integrates genetics, genomics, and molecular biology approaches to elucidate the pathogenesis of human diseases, and is intended to encourage students to unravel novel disease mechanism for improving management of human diseases.
  • Credits：3
  • Semester：Grade 1, First Semester
  • Language：English
  • Other：can be a credit of elective course for Translation Medical Group & Stem Cell Medicine Group

6. Biomedical statistics

  • Syllabus：To introduce the fundamental statistical issue in translational medicine.
  • Credits：2
  • Semester：Grade 1, Second Semester
  • Language：English

7. Stem cell biology

  • Syllabus：
    • This course will help students to establish the basic concepts on the topics of stem cell biology, research methodology and biomedical application.
    • The course will also introduce how phage display technique and CRISPR tools can be used in stem cell research.
    • In conjunction with the article reading, essay and presentation, this course will also build up students’ critical thinking and judgement on stem cell research.
  • Credits：3
  • Semester：Grade 2, First Semester
  • Language：English
  • Other：can be a credit of elective course for Translation Medical Group & Stem Cell Medicine Group

8. Dissertation

  • Syllabus：based on individual guidance professor.
  • Credits：12
  • Semester：Grade 2, Second Semester
  • Language：Chinese

Elective Course

1. Experimental design & research methods

  • Syllabus：Various research methods used in different fields of scientific research will be introduced, including basic principles of immunohistochemistry, western blotting, flow cytometry, PCR, real-time PCR, fluorescent and confocal microscopy, the use of in vivo and in vitro models, microarrays, microRNA assays, pharmacodynamic modeling, and proteomics.
  • Credits：2
  • Semester：Grade 1, First Semester
  • Language：English
  • Other：common course for college’s D. Program student

2. Animal models of human diseases

  • Syllabus：This course will give an introduction in the technology used to generate transgenic and knockout animal.
  • Credits：2
  • Semester：Grade 1, First Semester
  • Language：English

3. Epigenetics

  • Syllabus：
    • Epigenetics is a discipline of biology related to genetic changes in gene expression or cellular phenotype.
    • This class encourages students to familiar with the concepts and methods of epigenetics, and develops students” ability to apply this novel science to research.
  • Credits：2
  • Semester：Grade 1, First Semester
  • Language：English
  • Other：common course for college’s D. Program student

4. Medical decision support

  • Syllabus：Paper discussion on issues related to clinical decision support systems and project presentation
  • Credits：2
  • Semester：Grade 1, First Semester
  • Language：English
  • Other：common course for college’s D. Program student

5. Bioinformatics in precision medicine

  • Syllabus：
    • This course is to establish and familiarise graduates fundamental knowledge in bioinformatics. It includes genomics, proteomoics, transcriptomics, informatics, databases and high throughput data, such as microarray, GWAS and next generation sequencing.
    • After one semester studies in this course, the students will gain the basic bioinformatics domain knowledge and appreciate the significant meaning what rapidly progressing biotechnologies have brought to us and shaped our life.
  • Credits：2
  • Semester：Grade 1, First Semester
  • Language：English
  • Other：common course for college’s D. Program student

6. Stem cell translational research & therapeutics

  • Syllabus：
    • This course provides insights into both basic stem cell biology and clinical applications of stem cell-based cell replacement therapies for a variety of human diseases, including cardiovascular diseases, neurological disorders, and liver degeneration.
    • It also covers novel technologies for the culture and differentiation of both human embryonic stem cells and adult tissue stem cells.
    • In class lectures will be followed by student presentations of papers assigned by lecturer.
  • Credits：2
  • Semester：Grade 1, First Semester
  • Language：English
  • Other：common course for college’s D. Program student

7. Biological computing

  • Syllabus：
    • The aim of the course is to link issues in computer science to biology.
    • This course provides an introduction to the basic computational concepts and methods used in molecular biology and genetics.
    • It covers classic algorithmic techniques (e.g. divide and conquer algorithm, dynamic programming …), data structures (e.g. queue, tree…), and common computational problems in biology (e.g. motif finding, sequence alignment …).
    • In addition, Bioinformatics approaches for next generation sequencing and the most up-to-date technology will be addressed as well.
  • Credits：3
  • Semester：Grade 1, First Semester
  • Language：English
  • Other：course of Academia Sinica, only limited to students of our program

8. Experimental approaches in molecular & cell biology

  • Syllabus：This course provides the essential knowledge in the filed of molecular and cell biology, emphasizing on both the theory and the practical aspects.
  • Credits：2
  • Semester：Grade 1, First Semester
  • Language：English
  • Other：course of Academia Sinica, only limited to students of our program

9. Advanced tumor biology

  • Syllabus：
    • The biology of cancer is evolving due to the rapid expansion of both basic and medical sciences.
    • Students in this program should have a firm grasp of the most updated information in the field of cancer biology.
    • This course is intended to provide a comprehensive outlook of the newest findings in the field of cancer biology so that the students are prepared for their research projects as well as future career.
  • Credits：2
  • Semester：Grade 1, First Semester
  • Language：English

10. Special topics in chronic inflammation-associated cancers

  • Syllabus：
    • Association between chronic-inflammation and cancer development
    • understanding molecule mechanisms of cancer formation
  • Credits：2
  • Semester：Grade 1, First Semester
  • Language：English

11. Animal models of disease research

  • Syllabus：
    • The students will learn the induction abilities and surgery methods in disease animal model.
    • The neurological animal model will include spinal cord injury, Parkinson”s disease, traumatic brain injury and seizure.
  • Credits：2
  • Semester：Grade 1, First Semester
  • Language：English
  • Other：common course for college’s D. Program student

12. Precision genomics & proteomics in medical application

  • Syllabus： Students will understand the fundamental concepts of systems biology, will learn to utilize methods in multi-omics to elucidate the regulating mechanisms of biological phenomena, and to clarify clinical issues in human diseases and drug development in advance.
  • Credits：2
  • Semester：Grade 1, Second Semester
  • Language：Chinese

13. Machine Learning

  • Syllabus： Machine learning is a very critical technique for bioinformatics. With the release of various large biological data, we hope that we can “learn” underlying messages from the data using machine learning techniques. In this course I am going to introduce common algorithms and usages in the machine learning world and how to apply them on bioinformatics applications.
  • Credits：2
  • Semester：Grade 1, Second Semester
  • Language：English

14. Applied Biostatistics

  • Syllabus：
    • study design and design consideration of cohort study and longitudinal study
    • technology of collecting longitudinal data
    • various analysis method for longitudinal data
    • technology for handling missing data in longitudinal study.
  • Credits：2
  • Semester：Grade 1, Second Semester
  • Language：English

15. Cancer genomics & proteomics

  • Syllabus：The course will lead student to understand the cancer biology from genome to protein, introducing the technical method in cancer researches and also expecting students to have a better understanding of the current known mechanism of cancer through paper reading and group discussion.
  • Credits：2
  • Semester：Grade 1, Second Semester
  • Language：English

16. Biomedical science & drug development

  • Syllabus：
    • This course will introduce the progression of drug development from the view of molecular cellular biology and will make students understand the application of biomedical techniques, hoping to develop the ability of independent research and to make students understand the experiment design and pre-clinical trials in biomedical sciences.
    • Teachers will introduce how they find important issues and how they design experiments to prove the hypothesis.
  • Credits：2
  • Semester：Grade 1, Second Semester
  • Language：English

17. Special topics in ageing-associated diseases

  • Syllabus：
    • A lecture of ageing and ageing-related diseases is a closely related to everyone, but most of them still need to explore.
    • This course is designed to convey the mechanisms of ageing and animal models for ageing-related diseases, e.g., neurodegenerative diseases, muscle degenerative diseases, metabolic diseases.
    • In addition, this course also updates the medical application that will promote students well-understanding ageing-related research.
  • Credits：2
  • Semester：Grade 1, Second Semester
  • Language：English

18. Structural biology

  • Syllabus：
    • Structural biology focuses on obtaining and utilizing the three dimensional knowledge of macromolecules.
    • Not only does each specific structure of protein and nucleic acid provide information of how its biological functions are achieved, but how it interacts with other molecules is also an important basis for drug design.
    • By analyzing the structure of a known biological target, candidate drugs can be predicted and designed to bind with high affinity and selectivity to the target.
    • This course will discuss some recent achievements and hopefully open a door to structural biology and structure-based drug design investigation in the post-genomic era.
  • Credits：2
  • Semester：Grade 1, Second Semester
  • Language：English

19. Special topics in clinical medicine

  • Syllabus：
    • Understanding basic principles of the practice of medicine
    • Bridging the gap between the basic science and clinical medicine.
  • Credits：2
  • Semester：Grade 1, Second Semester
  • Language：English
  • Other：
    • Not a required course of MD
    • Course of Academia Sinica, only limited to students of our program

20. Modeling & analysis in genetics & genomics

  • Syllabus：This course will introduce fundamental concepts, statistical methods, and relevant software in human genetic and genomic studies.
  • Credits：2
  • Semester：Grade 2, First Semester
  • Language：English

21. Case study fortranslational medicine

  • Syllabus：
    • From the case study to learn the innovative strategy and the methods of promoting translational research to clinical applications.
    • Our course will included case studies, special lecture, and discussions in class based on the selected online open course.
  • Credits：2
  • Semester：Grade 2, First Semester
  • Language：English

22. Tumor microenvironment &clinical application

  • Syllabus：
    • We will first discuss the basic knowledge of tumor microenvironment.
    • Second, we will focus on the current advance research of tumor microenvironment.
    • With the combination of basic and advance discussion of tumor microenvironment, we hope student could develop a specific personal viewpoint regarding future translational development of tumor microenvironment in cancer therapies.
  • Credits：2
  • Semester：Grade 2, First Semester
  • Language：English

23. Nanotechnology application in medicine

  • Syllabus：This course includes various nanoparticles based therapeutics and related research methods.
  • Credits：2
  • Semester：Grade 2, First Semester

24. Bioinformatics

  • Syllabus：
    • This course is to establish and familiarize undergraduates fundamental knowledge in Bioinformatics.
    • It includes genomics, proteomics, informatics, databases, sequence alignment, gene expression and microarray, and systems biologics. ‘
    • After one semester studies in bioinformatics, the students will gain the basic bioinformatics domain knowledge and will be useful in their further specified disciplines in relative courses.
  • Credits：2
  • Semester：Grade 2, First Semester
  • Language：English
  • Other：common course for college’s D. Program student

25. Scientific writing

  • Syllabus：
    • The aim of this course is to train the graduated students in the Ph.D. program to be familiar with the format, content and skill of thesis and scientific writing, and to be able to evaluate the paper.
    • From these trainings, the student is expected to be able to design experiments for their research and to write manuscripts.
  • Credits：2
  • Semester：Grade 2, Second Semester
  • Language：English
  • Other：common course for college’s D. Program student
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